Pentobarbital
time:2015-07-29 15:25:47,count:0

Pentobarbital
Alias
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-
Barbituric acid, 5-ethyl-5-(1-methylbutyl)-
Category
Non-ionic surfactants-Amide
CAS No.
76-74-4
Molecular Formula & Molecular Weight
Molecular Formula: C11H18N2O3
Molecular Weight: 226.27
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: cat intravenous LD50: 72mg/Kg;
dog intravenous LD50: 50mg/Kg;
mouse intraperitoneal LD50: 75mg/Kg;
mouse intravenous LD50: 65mg/Kg;
mouse oral LD50: 170mg/Kg;
rabbit intravenous LD50: 33mg/Kg;
rabbit intraperitoneal LDLo: 65mg/Kg;
rabbit oral LDLo: 175mg/Kg;
rat intraperitoneal LD50: 108mg/Kg;
rat oral LD50: 125mg/Kg;
rat subcutaneous LD50: 144mg/Kg.
reproductive effect.
Human toxicity[1]: human oral LDLo: 36mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent hypnotic, sedative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 76-74-4