Amobarbital
time:2015-07-29 15:26:40,count:0

Amobarbital
Alias
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-
Barbituric acid, 5-ethyl-5-isopentyl-
Category
Non-ionic surfactants-Amide
CAS No.
57-43-2
Molecular Formula & Molecular Weight
Molecular Formula: C11H18N2O3
Molecular Weight: 226.27
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: cat oral LDLo: 100mg/Kg;
dog intravenous LD50: 58mg/Kg;
dog oral LDLo: 250mg/Kg;
mouse intraperitoneal LD50: 175mg/Kg;
mouse oral LD50: 345mg/Kg;
mouse subcutaneous LD50: 212mg/Kg;
rabbit intravenous LD50: 49mg/Kg;
rabbit oral LD50: 575mg/Kg;
rabbit intraperitoneal LDLo: 90mg/Kg;
rabbit subcutaneous LDLo: 170mg/Kg;
rat intraperitoneal LD50: 115mg/Kg;
rat oral LD50: 250mg/Kg;
rat subcutaneous LD50: 190mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent hypnotic, sedative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 57-43-2

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