Amobarbital sodium
time:2015-07-29 15:29:27,count:0

Amobarbital sodium
Alias
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-, monosodium salt
Barbituric acid, 5-ethyl-5-isopentyl-, sodium salt
Category
Anionic surfactants-Amide salt
CAS No.
64-43-7
Molecular Formula & Molecular Weight
Molecular Formula: C11H17NaN2O3
Molecular Weight: 248.25
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable. easily hydrolyzed.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: cat intraperitoneal LDLo: 90mg/Kg;
cat intravenous LDLo: 60mg/Kg;
dog intravenous LD50: 75mg/Kg;
dog oral LD50: 99mg/Kg;
dog rectal LDLo: 200mg/Kg;
frog oral LDLo: 110mg/Kg;
guinea pig intraperitoneal LDLo: 120mg/Kg;
guinea pig intravenous LDLo: 90mg/Kg;
guinea pig subcutaneous LDLo: 170mg/Kg;
mouse intraperitoneal LD50: 200mg/Kg;
mouse oral LD50: 505mg/Kg;
mouse subcutaneous LD50: 200mg/Kg;
mouse intravenous LDLo: 200mg/Kg;
rabbit intraperitoneal LD50: 90mg/Kg;
rabbit intravenous LD50: 70mg/Kg;
rabbit oral LD50: 575mg/Kg;
rabbit subcutaneous LDLo: 110mg/Kg;
rat intravenous LD50: 128mg/Kg;
rat oral LD50: 275mg/Kg;
rat intraperitoneal LDLo: 120mg/Kg;
rat subcutaneous LDLo: 90mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent hypnotic, sedative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 64-43-7