Dexamethasone
time:2015-07-31 22:17:24,count:0

Dexamethasone
Alias
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-
Category
Non-ionic surfactants-Alcohol
CAS No.
50-02-2
Molecular Formula & Molecular Weight
Molecular Formula: C22H29FO5
Molecular Weight: 392.46
Structural Formula
Properties
Appearance: solid.
Solubility: insoluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 410mg/Kg;
mouse subcutaneous LD50: 4400mg/Kg;
rabbit subcutaneous LD50: 7.2mg/Kg;
rat intraperitoneal LD50: 54mg/Kg;
rat oral LD50: > 3000mg/Kg;
rat subcutaneous LD50: 14mg/Kg.
reproductive effect.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-inflammatory, anti-allergic, emulsifying, dispersing abilities. Glucocorticoid.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 50-02-2

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