Valproic acid
time:2015-08-28 17:44:00,count:0

Valproic acid
Alias
Pentanoic acid, 2-propyl-
2-Propylvaleric acid
Category
Anionic surfactants-Carboxylate
CAS No.
99-66-1
Molecular Formula & Molecular Weight
Molecular Formula:C8H16O2
Molecular Weight:144.21
Structural Formula
Properties
Appearance: liquid.
Solubility: soluble in water, 20℃, 2g/L[1].
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: guinea pig oral LD50: 824mg/Kg;
mouse intraperitoneal LD50: 470mg/Kg;
mouse oral LD50: 1098mg/Kg;
mouse subcutaneous LD50: 860mg/Kg;
rabbit intraperitoneal LD50: 1200mg/Kg;
rat oral LD50: 670mg/Kg.
reproductive effect.
Human toxicity[1]: child oral TDLo: 375mg/Kg;
child oral TDLo: 412mg/Kg;
child oral TDLo: 10500mg/Kg/30;
human oral TDLo: 13.333mg/Kg/D-;
man oral LDLo: 736mg/Kg;
man oral TDLo: 21mg/Kg/2D-I;
man oral TDLo: 429mg/Kg;
women oral TDLo: 100mg/Kg/10D-;
women oral TDLo: 330mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anticonvulsant, dispersing, emulsifying, wetting abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 99-66-1

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