Sotalol hydrochloride
time:2015-08-29 16:50:46,count:0

Sotalol hydrochloride
Alias
Sotalol HCl
Methanesulfonanilide, 4'-(1-hydroxy-2-(isopropylamino)ethyl)-, monohydrochloride
Category
Non-ionic surfactants-Amine
CAS No.
959-24-0
Molecular Formula & Molecular Weight
Molecular Formula: C12H21ClN2SO3
Molecular Weight: 308.82
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intraperitoneal LD50: 330mg/Kg;
mouse intraperitoneal LD50: 670mg/Kg;
mouse oral LD50: 2600mg/Kg;
rabbit oral LD50: 1000mg/Kg;
rat intraperitoneal LD50: 680mg/Kg.
rat oral LD50: 3450mg/Kg.
Human toxicity[1]: human oral TDLo: 64mg/Kg/2W-I; man oral LDLo: 45.714mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-arrhythmia, emulsifying, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 959-24-0

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