Oxytetracycline
time:2015-09-07 13:35:31,count:0

Oxytetracycline
Alias
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-
Category
Non-ionic surfactants-Amine
CAS No.
79-57-2
Molecular Formula & Molecular Weight
Molecular Formula: C22H24N2O9
Molecular Weight: 460.43
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water, 25℃, 0.313g/L[1].
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intravenous LDLo: 220mg/Kg;
guinea pig intraperitoneal LDLo: 2250mg/Kg;
mouse intraperitoneal LD50: 5706mg/Kg;
mouse intravenous LD50: 140mg/Kg;
mouse oral LD50: 2240mg/Kg;
mouse subcutaneous LD50: 700mg/Kg;
rat intravenous LD50: 260mg/Kg;
rat oral LD50: 4800mg/Kg.
reproductive effect.
Human toxicity[1]: infant parenteral TDLo: 136mg/Kg;
man oral TDLo: 114mg/Kg/4D;
women oral TDLo: 24mg/Kg/6D-I.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, anti-infective abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 79-57-2

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