Time: 2012-09-27 17:26:17
Aluminum, hexadeca-mu-hydroxytetracosahydroxy(mu8-(1,3,4,6-tetra-O-sulfo-beta-D-fructofuranosyl alpha-D-glucopyranoside tetrakis(hydrogen sulfato)(8-)))hexadeca-;
Aluminum sucrose octasulfate;
Anionic Surfactant
>> Sulfate
>> Sugar Sulfate
>> Disaccharide Group Sulfate
>> Disaccharide Sulfate
Chemical Numbering System
Molecular Formula & Molecular Weight
Molecular Formula: C12H22O35S8.xAl
Molecular Weight: N/A
Schematic formula:
Appearance    (1), white to slightly yellow powder.
Solubility    slightly soluble in water; soluble in hydrochloric acid.
Hygroscopicity    hygroscopic.
Stability    stable in alkali, weak acid and hard water; unstable in strong acid, hydrolyzed.
Risk    Solid form: irritation, irritation to skin, eye.
GHS (Rev.6) label:  
Animal Toxicity
Table 1 Animal toxicity values
rat oral LD50
rat intraperitoneal LD50
rat subcutaneous LD50
mouse oral LD50
mouse intraperitoneal LD50
mouse subcutaneous LD50
Ecology    may be hazardous to environment. Water body should be given special attention.
Biodegradability    biodegradable.
Characteristics    excellent dispersing, emulsifying abilities.
Sucrose and chlorosulfonic acid react, then react with aluminum chlorohydrate, finally obtain product.
US patent 4,990,610 (Method for preparing high potency sucralfate) presents a synthetic process.
Quality Standards & Test Methods
1. Physical and chemical indexes
Physical and chemical indexes
Aluminum content,%, ≥
15.0 - 25.0
Sulfur content,%, ≥
5.0 - 15.0
Test Methods
(1), Aluminum content
Chinese Pharmacopoeia (2015 Edition) Sucralfate
(2), Sulfur content
Chinese Pharmacopoeia (2015 Edition) Sucralfate
2. Hazardous substances indexes
Hazardous substances indexes
Heavy metals (as Pb), mg/Kg, ≤
As, mg/Kg, ≤
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents - Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents - Determination of total arsenic
3. Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2015 Edition) Sucralfate
4. Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances; or furtherly test for microorganisms.
(c), Used in medicine, must comply with pharmacopoeia execution.
Major Uses
1. Personal care products
Conditioning agent in personal care products.
2. Medicine
Use as pharmaceutical composition (anti-ulcer agent, antacid). (The contents of this section are for reference only and should be subject to medical advice.)
[1]: ChemIDplus. 54182-58-0, Sucralfate
Update: 20130719(1); 20170220(2);