Menadione sodium bisulfite trihydrate
Time: 2017-12-05 20:43:22
Menadione sodium bisulfite trihydrate
Synonyms
Menadione sodium bisulfite;
2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt, trihydrate;
Category
Anionic Surfactant
>> Sulfonate
>> Quinonyl Sulfonate
>> Naphthoquinonyl Sulfonate
>> Linear alkyl Naphthoquinonyl Sulfonate
Chemical Numbering System
CASRN6147-37-1
EINECSN/A
Molecular Formula & Molecular Weight
Molecular Formula: C11H15NaO8S; C11H16O8S.Na
Molecular Weight: 330.29
Structure
Properties
Appearance    (1), solid.
Solubility    soluble in water.
Stability    stable. Light is easy to break down.
Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.6) label:  
Animal Toxicity
Table 1 Animal toxicity values
rat oral LD50
4507mg/kg[1]
rat intraperitoneal LD50
985mg/kg[1]
rat intravenous LD50
800mg/kg[1]
mouse intraperitoneal LD50
384mg/kg[1]
mouse oral LD50
1570mg/kg[1]
Ecology    may be hazardous to environment. Water body should be given special attention.
Biodegradability    biodegradable.
Characteristics    excellent wetting, dispersing abilities.
Synthesis
2-Methylnaphthoquinone reacts with sodium sulfite, then obtain.
Quality Standards & Test Methods
1. Physical and chemical indexes
Item
Physical and chemical indexes
Solid
Actives, %, ≥
60.0
pH (25°C, 1% solution)
< 6.0
Test Methods
(1), Actives
Chinese Pharmacopoeia (2015 Edition) Menadione sodium bisulfite
(2), pH
GB/T 6368 Surface active agents - Determination of pH of aqueous solution - Potentiometric method
ISO 4316 Surface active agents -- Determination of pH of aqueous solutions -- Potentiometric method
2. Hazardous substances indexes
Item
Hazardous substances indexes
Solid
Heavy metals (as Pb), mg/Kg, ≤
20
As, mg/Kg, ≤
3
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents - Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents - Determination of total arsenic
3. Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2015 Edition) Menadione sodium bisulfite
(1b), GB 7294 Feed additive - Vitamin K3 (menadione sodium bisulfite)
4. Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1. Medicine
Use as Use as pharmaceutical ingredient(Vitamin). (This section is for reference only, used in medicine, must comply with local pharmacopoeia execution.)
2. Feed
Use as feed additive.
Manufacturers
 
References
[1]: ChemIDplus. 6147-37-1, Menadione sodium bisulfite