Repagermanium
Time: 2018-06-04 22:15:14

Repagermanium

Synonyms

Propagermanium;

Poly-trans-((2-Carboxyethyl) Germasesquioxane);

Category

Special Surfactant

> Organogermanium

>> Anionic-type Organogermanium

>>> Carboxyalkyl Organogermanium

>>>> Carboxyl Linear Alkyl Organogermanium

Chemical Numbering System

CASRN12758-40-6

EINECS235-800-0

Molecular Formula & Molecular Weight

Molecular Formula: ((HOOCCH2CH2Ge)2O3)n

Molecular Weight: N/A

Structure

Properties

Appearance    (1), solid.

Solubility    soluble in water.

Stability    stable.

Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.

GHS (Rev.7) label:  

Animal Toxicity

Table 1 Animal toxicity values

dog oral LD

> 4000mg/kg[1]

mouse intraperitoneal LD50

1250mg/kg[1]

mouse intravenous LD50

> 200mg/kg[1]

mouse oral LD50

5600mg/kg[1]

mouse subcutaneous LD50

> 4000mg/kg[1]

rat intraperitoneal LD50

1670mg/kg[1]

rat intravenous LD50

> 200mg/kg[1]

rat oral LD50

7050mg/kg[1]

rat subcutaneous LD50

> 4000mg/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent antineoplastic, emulsifying, dispersing abilities.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Solid

Actives, %, ≥

95.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents - Detergents - Testing methods

GB/T 5173 Surface active agents and detergents-Determination of anionic-active matter by direct two-phase titration procedure

ISO 2271 Surface active agents -- Detergents -- Determination of anionic-active matter by manual or mechanical direct two-phase titration procedure

2, Hazardous substances indexes

Item

Hazardous substances indexes

Solid

Heavy metals (as Pb), mg/Kg, ≤

20

As, mg/Kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents - Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents - Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

(b), Used in cosmetics, should be test for harmful substances; or furtherly test for microorganisms.

Major Uses

1, Typical applications

Use as pharmaceutical ingredient.

2, Personal care products

Conditioning agent in personal care products.

3, Medicine

Use as pharmaceutical ingredient. (This section is for reference only, should be implemented according to local Pharmacopoeia.)

Manufacturers

 

References

[1]: ChemIDplus. 12758-40-6, Propagermanium