Carbenoxolone disodium
time:2012-10-09 17:23:27,count:0

Carbenoxolone disodium
Alias
Olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo, disodium salt, (3beta,20beta)-
Disodium Succinoyl Glycyrrhetinate
Category
Anionic surfactants-Carboxylate
CAS No.
7421-40-1
Molecular Formula & Molecular Weight
Molecular Formula: C34H48Na2O7
Molecular Weight: 614.72
Structural Formula
Properties
Appearance: white to pale yellow powder.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicology[1]: rat subcutaneous LD50: 1515mg/Kg;
rat oral LD50: 2450mg/Kg;
rat intraperitoneal LD50: 92mg/Kg;
mouse intravenous LD50: 198mg/Kg;
mouse intraperitoneal LD50: 120mg/Kg;
dog subcutaneous LD50: 1060mg/Kg;
dog oral LD50: 3900mg/Kg;
dog intraperitoneal LD50: 371mg/Kg.
Human toxicology[1]: human oral TDLo: 120mg/Kg/6W.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-inflammatory, anti-bacterial, anti-allergy, dispersing, emulsifying abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Conditioning agent in personal care products. good anti-inflammatory, anti-allergy, detoxification, whitening effects.
Use as a pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/:7421-40-1
Update: 20140309(1);

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