Diflucortolone valerate
Synonyms
6alpha,9-Difluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-valerate;
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16-methyl-21-((1-oxopentyl)oxy)-, (6-alpha,11-beta,16-alpha)-;
Diflucortolone 21-valerate;
Category
Non-ionic surfactant
> Ester
>> Alicyclic Alcohols Ester
>>> Steroid Ester
Chemical Numbering System
CASRN: 59198-70-8
EINECS: 261-655-8
Molecular Formula & Molecular Weight
Molecular Formula: C27H36F2O5
Molecular Weight: 478.57
Structure
Properties
Appearance (1), solid.
Solubility insoluble in water.
Stability stable. Under strong acid or strong alkali condition, easily hydrolyzed.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label:
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent lubricating, dispersing, emulsifying, anti-inflammatory abilities. Hormone.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
Item |
Physical and chemical indexes |
Solid |
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
Item |
Hazardous substances indexes |
Solid |
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as lubricant.
Use as dispersing agent, emulsion stabilizer.
Use as anti-inflammatory agent.
Manufacturers