Dimethicone
Synonyms
Polydimethylsiloxanes;
Polydimethylsiloxane;
Poly(oxy(dimethylsilylene));
Polydimethyl siloxane;
Silicones and siloxanes, dimethyl;
PDMS;
Category
Silicone Surfactant
> Non-ionic Silicone Surfactant
>> Alkyl (Substituted Alkyl) Silicone Polymer
Chemical Numbering System
CASRN: 9006-65-9 / 9016-00-6 / 63148-62-9
EINECS: N/A / N/A / N/A
Molecular Formula & Molecular Weight
Molecular Formula: N/A
Molecular Weight: N/A
Structure
Properties
Appearance (1), colorless liquid to solid; or emulsion.
Solubility insoluble in water.
Stability stable.
Risk Liquid (or solid) form: irritation, irritation to skin, eye, respiratory system.
GHS (Rev.10) label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog intraperitoneal LD |
> 410mg/kg[2] |
|
dog intrapleural LD |
> 410mg/kg[2] |
|
dog subcutaneous LD |
> 410mg/kg[2] |
|
guinea pig oral LD |
> 10000mg/kg[3] |
|
mouse intraperitoneal LD |
> 5500mg/kg[2] |
|
mouse intraperitoneal LDLo |
16mL/kg[3] |
|
mouse intrapleural LD |
> 5500mg/kg[2] |
|
mouse oral LD50 |
> 20000mg/kg[1] |
|
mouse subcutaneous LD |
> 5500mg/kg[2] |
|
rabbit inhalation LC |
> 978000mg/m3/7.5[3] |
|
rabbit skin LD |
> 20mL/kg[3] |
|
rabbit skin LD |
> 10200mg/kg[3] |
|
rabbit skin LD |
> 2000mg/kg[3] |
|
rat intramuscular LD |
> 1.2mL/kg[3] |
|
rat intraperitoneal LD |
> 2000mg/kg[2] |
|
rat intrapleural LD |
> 2000mg/kg[2] |
|
rat oral LD |
> 5000mg/kg[3] |
|
rat oral LD |
> 50mL/kg[3] |
|
rat oral LD50 |
> 17000mg/kg[3] |
|
rat oral LD50 |
> 24000mg/kg[3] |
|
rat subcutaneous LD |
> 2000mg/kg[2] |
Reproductive effect[2,3].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent film-forming, lubricating, antistatic, dispersing, adsorbing abilities. Nonmetallic elastomer.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid / Solid |
|
|
Actives, %, ≥ |
30.0-100.0 / 95.0 |
Test Methods
(1), Actives
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid/Solid |
|
|
Heavy metals (as Pb), mg/Kg, ≤ |
20 |
|
As, mg/Kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 30612 Food safety national standard -- Food additive -- Polydimethyl siloxane and emulsion
(1b), HG/T 2366 Dimethicone
(1c), Chinese Pharmacopoeia (2020 Edition) Dimethicone
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as film-forming agent.
Use as lubricant, mold-release agent.
Use as anti-foaming agent.
Use as sealant.
Use as non-metal material. For example, used in lenses, bio-engineering.
2, Personal care products
Conditioning agent, emollient, defoaming agent, skin protective agent in personal care products. Non-cumulative.
3, Textile, fiber, leather
Softening agent, antistatic agent, brightening agent in textile, fiber, leather.
4, Food
Use as food additive (coating agent).
5, Medicine
Pharmaceutical excipient, use as anti-foaming agent, lubricant. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 9006-65-9, Dimethicone
[2]: ChemIDplus. 9016-00-6, Polydimethylsiloxane
[3]: ChemIDplus. 63148-62-9, Siloxanes and Silicones, di-Me
Update: 20140828(1); 20200913(2);