Chlorhexidine
time:2012-12-08 15:06:32,count:0

Chlorhexidine
Alias
2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-
Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-
Category
Non-ionic surfactants-Amine
CAS No.
55-56-1
Molecular Formula & Molecular Weight
Molecular Formula: C22H30Cl2N10
Molecular Weight: 505.45
Structural Formula
Properties
Appearance: white solid.
Solubility: slightly soluble in water; 20℃, 0.8g/L[1].
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 44mg/Kg;
mouse intravenous LD50: 24mg/Kg;
mouse oral LD50: 2515mg/Kg;
mouse subcutaneous LD50: 632mg/Kg;
rabbit intravenous LD: >8mg/Kg;
rat intraperitoneal LD50: 60mg/Kg;
rat intravenous LD50: 21mg/Kg;
rat oral LD50: 9.2mL/Kg;
rat subcutaneous LD50: >1000mg/Kg.
Reproductive effect.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, preservative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Widely use as bactericide, preservatives.
Bactericide, preservatives, oral care agent in personal care products. eg: mouthwash.
Bactericide, preservatives in medicine.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 55-56-1
Update: 20130924(1);

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