Chlorhexidine digluconate
time:2012-12-08 15:07:28,count:0

Chlorhexidine digluconate
Alias
Chlorhexidine gluconate
2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, di-D-gluconate
Category
Non-ionic surfactants-Amine
CAS No.
18472-51-0
Molecular Formula & Molecular Weight
Molecular Formula: C34H54Cl2N10O14
Molecular Weight: 897.76
Structural Formula
Properties
Appearance: (1), white solid; (2), liquid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intravenous LD50: 12.9mg/Kg;
mouse oral LD50: 1260mg/Kg;
mouse subcutaneous LD50: 1140mg/Kg;
rat intravenous LD50: 24.2mg/Kg;
rat oral LD50: 2000mg/Kg;
rat subcutaneous LD50: 3320mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, preservative abilities. do not contact with metal. eg: iron, aluminum.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Widely use as bactericide, preservatives.
Bactericide, preservatives, oral care agent in personal care products. eg: mouthwash.
Bactericide, preservatives in medicine.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 18472-51-0
Update: 20130924(1);

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