Ciclopirox olamine
time:2012-12-10 05:58:06,count:0

Ciclopirox olamine
Alias
2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-, compd. with 2-aminoethanol (1:1)
6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
Category
Non-ionic surfactants-Amide
CAS No.
41621-49-2
Molecular Formula & Molecular Weight
Molecular Formula: C14H24N2O3
Molecular Weight: 268.35
Structural Formula
Properties
Appearance: white powder.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 83mg/Kg;
mouse intravenous LD50: 71mg/Kg;
mouse oral LD50: 1740mg/Kg;
mouse subcutaneous LD50: 1730mg/Kg;
rabbit oral LD50: > 3065mg/Kg;
rat intraperitoneal LD50: 146mg/Kg;
rat intravenous LD50: 72mg/Kg;
rat oral LD50: 2350mg/Kg;
rat subcutaneous LD50: > 2500mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, preservative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Bactericide, antidandruff agent in personal care products.
Antifungal agent in medicine.
Use as bactericide, preservative.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/:41621-49-2
Update: 20130918(1);

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