Tolnaftate
time:2013-04-17 01:00:30,count:0
Tolnaftate
Alias
Carbamothioic acid, N-methyl-N-(3-methylphenyl)-, O-2-naphthalenyl ester
Category
Non-ionic surfactants-Esters
CAS No.
2398-96-1
Molecular Formula & Molecular Weight
Molecular Formula: C19H17NOS
Molecular Weight: 307.41
Structural Formula
Properties
Appearance: solid.
Solubility: insoluble in water.
Stability: stable. at strong acid, strong alkali, easily hydrolyzed.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog oral LD50: > 14000mg/Kg;
guinea pig oral LD50: > 4000mg/Kg;
mouse intraperitoneal LD50: 120mg/Kg;
mouse intravenous LD50: 4800mg/Kg;
mouse oral LD50: 10000mg/Kg;
mouse subcutaneous LD50: > 6000mg/Kg;
rabbit intravenous LD: > 50mg/Kg;
rat oral LD50: > 6000mg/Kg;
rat subcutaneous LD50: > 4000mg/Kg.
reproductive effect.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, preservative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as fungicide.
Fungicide in personal care products.
Use as pharmaceutical composition.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 2398-96-1
Update: 20141014(1);

 

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