Sodium salicylate
time:2013-06-16 09:49:50,count:0
Sodium salicylate
Alias
Benzoic acid, 2-hydroxy-, sodium salt (1:1)
Salicylic acid, monosodium salt
Category
Anionic surfactants-Carboxylate
CAS No.
54-21-7
Molecular Formula & Molecular Weight
Molecular Formula:C7H5NaO3
Molecular Weight:160.10
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable. easily oxidized.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intravenous LD50: 562mg/Kg;
dog intraperitoneal LDLo: 990mg/Kg;
dog oral LDLo: 450mg/Kg;
dog subcutaneous LDLo: 200mg/Kg;
frog subcutaneous LDLo: 250mg/Kg;
guinea pig intraperitoneal LDLo: 900mg/Kg;
guinea pig subcutaneous LDLo: 800mg/Kg;
mouse intramuscular LD50: 760mg/Kg;
mouse intraperitoneal LD50: 500mg/Kg;
mouse intravenous LD50: 500mg/Kg;
mouse oral LD50: 540mg/Kg;
mouse subcutaneous LD50: 550mg/Kg;
rabbit intravenous LD50: 415mg/Kg;
rabbit oral LD50: 1700mg/Kg;
rat intraperitoneal LD50: 542mg/Kg;
rat oral LD50: 930mg/Kg.
reproductive effect.
Human toxicity[1]: Human oral LDLo: 700mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-inflammatory, preservative, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Preservative in personal care products.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 54-21-7
Update: 20140309(1);

 

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