Hydrocortisone sodium succinate
time:2013-06-17 01:57:42,count:0
Hydrocortisone sodium succinate
Alias
Cortisol, 21-(hydrogen succinate), monosodium salt
Hydrocortisone 21-(sodium succinate)
Category
Anionic surfactants-Carboxylate
CAS No.
125-04-2
Molecular Formula & Molecular Weight
Molecular Formula:C25H33NaO8
Molecular Weight:484.51
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 1050mg/Kg;
rat intraperitoneal LD50: 1320mg/Kg.
reproductive effect.
Human toxicity[1]: man intravenous LDLo: 1.429mg/Kg; man intravenous TDLo: 2.857mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-inflammatory, emulsifying, dispersing, lubricating abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as emulsifying agent, dispersing agent.
Use as lubricant.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 125-04-2
Update: 20140330(1);

 

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