Hexachlorophene
time:2013-07-29 03:03:25,count:0

Hexachlorophene
Alias
2,2'-Methylenebis(3,4,6-trichlorophenol)
Category
Non-ionic surfactants-Phenol
CAS No.
70-30-4
Molecular Formula & Molecular Weight
Molecular Formula: C13H6Cl6O2
Molecular Weight: 406.90
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]:dog intravenous LDLo: 5mg/Kg;
dog oral LDLo: 40mg/Kg;
guinea pig oral LD50: 60mg/Kg;
guinea pig skin LD50: 1100mg/Kg;
guinea pig intraperitoneal LDLo: 25mg/Kg;
mouse inhalation LC50: 290mg/m3;
mouse intraperitoneal LD50: 20mg/Kg;
mouse oral LD50: 67mg/Kg;
mouse skin LD50: 270mg/Kg;
mouse subcutaneous LD50: 46mg/Kg;
rabbit intravenous LD50: 8.5mg/Kg;
rabbit oral LD50: 40.69mg/Kg;
rat inhalation LC50: 340mg/m3;
rat intraperitoneal LD50: 22mg/Kg;
rat intravenous LD50: 7.5mg/Kg;
rat oral LD50: 56mg/Kg;
rat skin LD50: 1840mg/Kg;
rat subcutaneous LD50: 7.65mg/Kg.
reproductive effect.
Human toxicity [1]: child oral LDLo:250mg/Kg;
infant oral TDLo: 257mg/kg/7D-I;
women oral TDLo: 600mg/Kg.
overall carcinogenic evaluation: Group 3.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, preservative, dispersing abilities.
Notes: do not use in products of infants and children.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as antimicrobial agent, antibacterial agent, preservatives, disinfectant.
Preservatives in personal care products.
Use as wood preservatives.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 70-30-4

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