Diphenhydramine
time:2013-08-10 01:05:10,count:0

Diphenhydramine
Alias
Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-
Category
Non-ionic surfactants-Amine
CAS No.
58-73-1
Molecular Formula & Molecular Weight
Molecular Formula: C17H21NO
Molecular Weight: 255.35
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: guinea pig intraperitoneal LD50: 75mg/Kg;
guinea pig subcutaneous LD50: 56mg/Kg;
mouse intraperitoneal LD50: 56mg/Kg;
mouse intravenous LD50: 29mg/Kg;
mouse oral LD50: 160mg/Kg;
mouse subcutaneous LD50: 50mg/Kg;
rat intraperitoneal LD50: 280mg/Kg;
rat intravenous LD50: 42mg/Kg;
rat oral LD50: 390mg/Kg;
rat subcutaneous LD50: 474mg/Kg.
reproductive effect.
Human toxicity[1]: human oral TDLo: 0.714mg/Kg;
women oral TDLo: 30mg/Kg;
women oral TDLo: 82mg/Kg;
women oral TDLo: 178mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antistatic, dispersing, emulsifying, anticorrosive abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as antistatic agent.
Use as dispersing agent, emulsifying agent.
Conditioning agent in personal care products.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 58-73-1

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