MEA-Benzoate
Synonyms
Benzoic acid, compound with 2-aminoethanol (1:1);
Monoethanolamine benzoate;
Category
Anionic Surfactant
> Carboxylate
>> Cyclic Carboxylate
>>> Aryl Carboxylate
>>>> Benzoate
Chemical Numbering System
CASRN：4337-66-0
EINECS：224-387-2
Molecular Formula & Molecular Weight
Molecular Formula: C9H13NO3; C7H6O2.C2H7N1O
Molecular Weight: 183.20
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse oral LD50 |
2680mg/kg[1] |
|
rat oral LD50 |
9274mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, preservative, anticorrosive, dispersing, emulsifying abilities.
Note (1), Should not be used in children products that can be direct prolonged contact with the skin, such as skin care products.
(2), Avoid using in children cleaning products, such as shampoos.
(3), Do not use in nitrosating environment. Reaction of monoethanolamine and nitrous acid can not produce nitrosamines, however, reaction of contained secondary amine of monoethanolamine and nitrous acid can produce nitrosamines. Nitrosamine is a carcinogen.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents - Detergents - Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/Kg, ≤ |
20 |
|
As, mg/Kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents - Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents - Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as preservative.
2, Personal care products
Preservative in personal care products.
* * * * * *
Further information:
(1), (1a), In accordance with EU regulations (EC) No 1223/2009, directive 2007/17/EC, be included in Annex V/1a.
Maximum concentration is 0.5% (as acid).
(1b), In accordance with EU regulations (EC) No 1223/2009, directive 2003/83/EC, be included in Annex III/61.
Maximum concentration of secondary amine is 0.5% in products.
In raw materials, maximum secondary amine content is 0.5%.
Maximum nitrosamine content is 50μg/kg.
The container is nitrite-free.
When used, the requirements of (1a) and (1b) must be satisfied.
(2), (2a), In accordance with Safety and Technical Standards for Cosmetics (2015 Edition) of China, be included in the allowed preservatives.
Maximum concentration is 0.5% (as acid).
(2b), In accordance with Safety and Technical Standards for Cosmetics (2015 Edition) of China, be included in the restricted components.
In raw materials, maximum secondary amine content is 0.5%.
Maximum nitrosamine content is 50μg/kg.
The container is nitrite-free.
When used, the requirements of (2a) and (2b) must be satisfied.
3, Industrial cleaning agents
Use as corrosion inhibitor.
Manufacturers
References
[1]: ChemIDplus. 4337-66-0, Ethanolamine benzoate
Update: 20140309(1); 20181112(2);