Thiamine HCl
time:2013-08-28 02:51:49,count:0

Thiamine HCl
Alias
Thiamine hydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1), hydrochloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride, monohydrochloride
Vitamin B1 hydrochloride
Category
Cationic surfactants-Quaternary ammonium salts
CAS No.
67-03-8
Molecular Formula & Molecular Weight
Molecular Formula: C12H18Cl2N4SO
Molecular Weight: 337.27
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, strong irritation to skin, eye.
Animal toxicity[1]: cat intravenous LD50: 75mg/Kg;
frog subcutaneous LD50: 2600mg/Kg;
guinea pig intravenous LD50: 140mg/Kg;
guinea pig subcutaneous LD50: 872mg/Kg;
mouse intraperitoneal LD50: 200mg/Kg;
mouse intravenous LD50: 74mg/Kg;
mouse oral LD50: 8224mg/Kg;
mouse subcutaneous LD50: 266mg/Kg;
pigeon intravenous LD50: 180mg/Kg;
rabbit intravenous LD50: 117mg/Kg;
rat intraperitoneal LD50: 481mg/Kg;
rat intravenous LD50: 118mg/Kg;
rat oral LD50: 3710mg/Kg;
rat subcutaneous LD50: 560mg/Kg.
Human toxicity[1]: women intramuscular LDLo: 5mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antistatic, dispersing, emulsifying abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
90
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as antistatic agent.
Conditioning agent in personal care products.
Use as emulsifying agent, dispersing agent.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 67-03-8

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