Quinine
time:2013-09-15 07:00:25,count:0

Quinine
Alias
(8S,9R)-6'-Methoxycinchonan-9-ol
Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-
Category
Non-ionic surfactants-Amine
CAS No.
130-95-0
Molecular Formula & Molecular Weight
Molecular Formula: C20H24N2O2
Molecular Weight: 324.42
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable. easily oxidized.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: cat intravenous LDLo: 100mg/Kg;
cat subcutaneous LDLo: 100mg/Kg;
dog subcutaneous LDLo: 180mg/Kg;
frog intramuscular LDLo: 400mg/Kg;
frog oral LDLo: 1500mg/Kg;
frog subcutaneous LDLo: 200mg/Kg;
guinea pig oral LD50: 1800mg/Kg;
mouse intraperitoneal LD50: 115mg/Kg;
mouse intravenous LD50: 68mg/Kg;
mouse subcutaneous LDLo: 200mg/Kg;
pigeon intramuscular LDLo: 500mg/Kg;
rabbit intravenous LDLo: 70mg/Kg;
rabbit oral LDLo: 500mg/Kg;
rabbit subcutaneous LDLo: 231mg/Kg;
rat intraperitoneal LD: > 100mg/Kg;
rat oral LDLo: 800mg/Kg;
rat subcutaneous LDLo: 200mg/Kg.
reproductive effect.
Human toxicity[1]: women oral TDLo: 74mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-infective, antibacterial, emulsifying, dispersing, antistatic abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
90
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as antistatic agent.
Denaturant, conditioning agent, masking agent in personal care products.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 130-95-0

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