Miconazole
time:2013-12-02 17:10:47,count:0

Miconazole
Alias
1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-
Category
Non-ionic surfactants-Amine
CAS No.
22916-47-8
Molecular Formula & Molecular Weight
Molecular Formula: C18H14Cl4N2O
Molecular Weight: 416.13
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intravenous LD50: 60mg/Kg;
mouse intraperitoneal LD50: 220mg/Kg;
mouse intravenous LD50: 80mg/Kg;
mouse oral LD50: 519mg/Kg;
rat intraperitoneal LD50: 349mg/Kg;
rat intravenous LD50: 105mg/Kg;
rat oral LD50: 550mg/Kg.
reproductive effect.
Human toxicity[1]: infant intravenous TDLo: 104mg/kg/4D-I.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial, preservative abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as antimicrobial agent.
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 22916-47-8

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