Lidocaine
time:2013-12-02 19:54:15,count:0

Lidocaine
Alias
Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-
2',6'-Acetoxylidide, 2-(diethylamino)-
Category
Non-ionic surfactants-Amine
CAS No.
137-58-6
Molecular Formula & Molecular Weight
Molecular Formula: C14H22N2O
Molecular Weight: 234.34
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: guinea pig LD50: 120mg/Kg;
guinea pig intravenous LDLo: 65mg/Kg;
mouse intraperitoneal LD50: 102mg/Kg;
mouse intravenous LD50: 20mg/Kg;
mouse oral LD50: 220mg/Kg;
mouse subcutaneous LD50: 238mg/Kg;
rabbit intravenous LDLo: 41mg/Kg;
rat intraperitoneal LD50: 133mg/Kg;
rat intravenous LD50: 18mg/Kg;
rat oral LD50: 317mg/Kg;
rat subcutaneous LD50: 335mg/Kg.
Human toxicity[1]: child oral TDLo: 21mg/Kg;
child oral TDLo: 300mg/Kg/5D-I;
human intravenous TDLo: 23mg/Kg;
man intravenous TDLo: 1.7mg/Kg/2M-;
man intravenous TDLo: 8.643mg/Kg/4H-;
women intraspinal TDLo: 1mL/Kg;
women intravenous TDLo: 16mg/Kg;
women oral TDLo: 39mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antistatic, dispersing, emulsifying abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Conditioning agent in personal care products.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 137-58-6

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