Clobetasol propionate
time:2015-02-08 16:58:05,count:0

Clobetasol propionate
Alias
Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11beta,16beta)-
Category
Non-ionic surfactants-Alcohol
CAS No.
25122-46-7
Molecular Formula & Molecular Weight
Molecular Formula: C25H32ClFO5
Molecular Weight: 466.97
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 118mg/Kg;
mouse oral LD50: > 3000mg/Kg;
mouse subcutaneous LD50: 81.7mg/Kg;
rat intraperitoneal LD50: 351mg/Kg;
rat oral LD50: > 3000mg/Kg;
rat subcutaneous LD50: 366mg/Kg.
reproductive effect.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent emulsifying, dispersing, anti-inflammatory abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as dispersing agent, emulsion stabilizer.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 25122-46-7

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