Trazodone hydrochloride
time:2015-04-03 21:50:25,count:0


Trazodone hydrochloride
1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride
Non-ionic surfactants-Amine
Molecular Formula & Molecular Weight
Molecular Formula: C19H23Cl2N5O
Molecular Weight: 408.32
Structural Formula
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intravenous LD50: > 40mg/Kg;
dog oral LD50: 500mg/Kg;
monkey intravenous LD50: 25mg/Kg;
mouse intraperitoneal LD50: 255mg/Kg;
mouse intravenous LD50: 91mg/Kg;
mouse oral LD50: 584mg/Kg;
mouse subcutaneous LD50: > 1500mg/Kg;
rabbit intravenous LD50: 52mg/Kg;
rabbit oral LD50: 560mg/Kg;
rat intraperitoneal LD50: 178mg/Kg;
rat intravenous LD50: 91mg/Kg;
rat oral LD50: 690mg/Kg;
rat subcutaneous LD50: 2729mg/Kg.
reproductive effect.
Human toxicity[1]: man oral TDLo: 0.667mg/Kg;
man oral TDLo: 5.714mg/Kg/4D-;
man oral TDLo: 43mg/Kg/30D-I;
man oral TDLo: 46mg/Kg/8D-I;
women oral TDLo: 0.75mg/Kg;
women oral TDLo: 80mg/Kg;
women oral TDLo: 100mg/Kg;
women oral TDLo: 720mg/Kg/34W-.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent dispersing, antistatic, emulsifying abilities.
Quality standards & test methods
physical and chemical indexes
test methods
actives*, %, ≥
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as emulsifying agent, dispersing agent.
Use as antistatic agent.
[1]: 25332-39-2


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