Prazosin hydrochloride
time:2015-04-10 21:37:16,count:0

Prazosin hydrochloride
Alias
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-, monohydrochloride
Category
Non-ionic surfactants-Amine
CAS No.
19237-84-4
Molecular Formula & Molecular Weight
Molecular Formula: C19H22ClN5O4
Molecular Weight: 419.86
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog oral LD50: > 700mg/Kg;
mouse intraperitoneal LD50: 60mg/Kg;
mouse intravenous LD50: 92mg/Kg;
mouse oral LD50: 5000mg/Kg;
mouse subcutaneous LD50: 3100mg/Kg;
rat intraperitoneal LD50: 102mg/Kg;
rat intravenous LD50: 73mg/Kg;
rat oral LD50: 1950mg/Kg;
rat subcutaneous LD50: 3750mg/Kg;
reproductive effect.
Human toxicity[1]: human oral TDLo: 0.285mg/Kg;
man oral TDLo: 1.714mg/Kg;
women oral TDLo: 0.01mg/Kg;
women oral TDLo: 13mg/Kg/6W-I.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent dispersing, antistatic abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 19237-84-4

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