Clindamycin hydrochloride
time:2015-04-14 17:28:14,count:0

Clindamycin hydrochloride
Alias
Clindamycin HCl
L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-, monohydrochloride
Category
Non-ionic surfactants-Sugar
CAS No.
21462-39-5
Molecular Formula & Molecular Weight
Molecular Formula: C18H34Cl2N2SO5
Molecular Weight: 461.44
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intramuscular LD50: 1100mg/Kg;
mouse intraperitoneal LD50: 361mg/Kg;
mouse intravenous LD50: 245mg/Kg;
mouse oral LD50: 2539mg/Kg;
mouse subcutaneous LD50: 1036mg/Kg;
rat intramuscular LD50: 273mg/Kg;
rat intraperitoneal LD50: 745mg/Kg;
rat oral LD50: 2193mg/Kg;
rat subcutaneous LD50: 2618mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
90
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Use as antimicrobial agent, antibacterial agent.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 21462-39-5

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