Diflunisal
time:2015-04-22 15:28:43,count:0

Diflunisal
Alias
(1,1'-Biphenyl)-3-carboxylic acid, 2',4'-difluoro-4-hydroxy-
3-Biphenylcarboxylic acid, 2',4'-difluoro-4-hydroxy-
Category
Anionic surfactants-Carboxylate
CAS No.
22494-42-4
Molecular Formula & Molecular Weight
Molecular Formula:C13H8F2O3
Molecular Weight:250.20
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 124mg/Kg;
mouse oral LD50: 439mg/Kg;
mouse subcutaneous LD50: 212mg/Kg;
rabbit oral LD50: 603mg/Kg;
rat intraperitoneal LD50: 159mg/Kg;
rat oral LD50: 392mg/Kg;
rat subcutaneous LD50: 185mg/Kg.
reproductive effect.
Human toxicity[1]: human oral TDLo: 71mg/Kg/5D-I; man oral TDLo: 429mg/kg/17W-.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-inflammatory, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 22494-42-4

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