Ipratropium bromide
time:2015-04-24 22:20:23,count:0

Ipratropium bromide
Alias
8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy) -8-methyl-8-(1-methylethyl)-, bromide, (3-endo,8-syn)-
Category
Cationic surfactants-Quaternary ammonium salts
CAS No.
22254-24-6
Molecular Formula & Molecular Weight
Molecular Formula: C20H30BrNO3
Molecular Weight: 412.36
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog oral LD50: 1300mg/Kg;
dog intravenous LDLo: 20mg/Kg;
mouse intraperitoneal LD50: 72mg/Kg;
mouse intravenous LD50: 12.29mg/Kg;
mouse oral LD50: 1001mg/Kg;
mouse subcutaneous LD50: 300mg/Kg;
rabbit oral LD50: 1557mg/Kg;
rat intraperitoneal LD50: 113mg/Kg;
rat intravenous LD50: 15.7mg/Kg;
rat oral LD50: 1663mg/Kg;
rat subcutaneous LD50: 635mg/Kg.
reproductive effect.
Human toxicity[1]: man inhalation TCLo: 0.001mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antistatic, dispersing, emulsifying abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 22254-24-6

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