Epirubicin hydrochloride
time:2015-04-30 18:17:12,count:0

Epirubicin hydrochloride
Alias
Epidoxorubicin hydrochloride
Epirubicin HCl
5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)-
Category
Non-ionic surfactants-Sugar
CAS No.
56390-09-1
Molecular Formula & Molecular Weight
Molecular Formula: C27H30ClNO11
Molecular Weight: 579.98
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intravenous LD50: 2.25mg/Kg;
mouse intravenous LD50: 31.5mg/Kg;
mouse oral LD50: > 2000mg/Kg;
mouse subcutaneous LD50: 37.5mg/Kg;
rat intraperitoneal LD50: 10.8mg/Kg;
rat intravenous LD50: 17mg/Kg;
rat oral LD50: 1350mg/Kg;
rat subcutaneous LD50: 17.6mg/Kg.
Human toxicity[1]: women intravenous TDLo: 1622mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antineoplastic, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 56390-09-1

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