Streptozocin
time:2015-05-01 13:49:12,count:0

Streptozocin
Alias
Streptozotocin
D-Glucopyranose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)-
D-Glucose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)-
Category
Non-ionic surfactants-Sugar
CAS No.
18883-66-4
Molecular Formula & Molecular Weight
Molecular Formula: C8H15N3O7
Molecular Weight: 265.22
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog intravenous LD50: 50mg/Kg;
monkey intravenous LDLo: 80mg/Kg;
mouse intraperitoneal LD50: 360mg/Kg;
mouse intravenous LD50: 275mg/Kg;
mouse parenteral LD50: 264mg/Kg;
mouse subcutaneous LD50: 335mg/Kg;
rat intravenous LD50: 138mg/Kg.
reproductive effect.
Human toxicity[1]: human intravenous TDLo: 1044mg/Kg/5D;
women intravenous LDLo: 440mg/Kg/65W-;
women intravenous TDLo: 13.513mg/Kg.
overall carcinogenic evaluation: Group 2B.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antineoplastic, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 18883-66-4

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