Bromelain
Time: 2015-05-26 15:00:32; Reading: 4

Bromelain

Synonyms

EC 3.4.22.4;

Category

Special Surfactant

> Enzyme

Chemical Numbering System

CASRN9001-00-7

EINECS232-572-4

Molecular Formula & Molecular Weight

Molecular Formula: N/A

Molecular Weight: N/A

Structure

 

Properties

Appearance    (1), white to brown-yellow amorphous powder.

Solubility    soluble in water.

Stability    stable.

Risk    Solid form: irritation, irritation to skin, eye, respiratory system.

GHS (Rev.8) label: 

Animal Toxicity

Table 1 Animal toxicity values

mouse intraperitoneal LD50

36.7mg/kg[1]

mouse intravenous LD50

30mg/kg[1]

mouse oral LD50

> 10000mg/kg[1]

rabbit intravenous LD50

20mg/kg[1]

rat intraperitoneal LD50

85.2mg/kg[1]

rat oral LD50

> 10000mg/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent catalytic, anti-inflammatory abilities. Thiol protease.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Enzyme activity, U, ≥

 

Test Methods

(1), Enzyme activity

 

2, Hazardous substances indexes

Item

Hazardous substances indexes

Heavy metals (as Pb), mg/Kg, ≤

30

As, mg/Kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

GB 5009.74 Food safety national standard -- Method for limit test of heavy metals in food additives

GB 5009.12 Food safety national standard -- Determination of lead in foods

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents - Determination of heavy metals

(2), As

GB 5009.11 Food safety national standard -- Determination of total arsenic and abio-arsenic in foods

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents - Determination of total arsenic

3, Further explanation

(a), Used in cosmetics, should be test for harmful substances; or furtherly test for microorganisms.

Major Uses

1, Typical applications

Use as catalyst.

2, Personal care products

Conditioning agent, keratolytic agent in personal care products.

3, Food

Use as food additive.

Manufacturers

 

References

[1]: ChemIDplus. 9001-00-7, Bromelain

Update: 20180815(1);