Digoxin
time:2015-06-22 18:56:52,count:0

Digoxin
Alias
Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
Category
Non-ionic surfactants-Sugar
CAS No.
20830-75-5
Molecular Formula & Molecular Weight
Molecular Formula: C41H64O14
Molecular Weight: 780.94
Structural Formula
Properties
Appearance: solid.
Solubility: slightly soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: cat oral LD50: 0.2mg/Kg;
cat intraduodenal LDLo: 0.441mg/Kg;
cat intravenous LDLo: 0.159mg/Kg;
cat parenteral LDLo: 1.47mg/Kg;
dog intravenous LDLo: 0.2mg/Kg;
dog oral LDLo: 0.3mg/Kg;
frog subcutaneous LD50: 0.00224mg/Kg;
frog parenteral LDLo: 1mg/Kg;
guinea pig intraduodenal LD50: 3.2mg/Kg;
guinea pig intramuscular LD50: 0.63mg/Kg;
guinea pig intraperitoneal LD50: 0.8mg/Kg;
guinea pig oral LD50: 3.5mg/Kg;
guinea pig subcutaneous LD50: 0.6mg/Kg;
guinea pig intravenous LDLo: 0.468mg/Kg;
mouse intracerebral LD50: 0.124mg/Kg;
mouse intraperitoneal LD50: 3.964mg/Kg;
mouse intravenous LD50: 7.67mg/Kg;
mouse oral LD50: 17.78mg/Kg;
mouse subcutaneous LD50: 0.00815mg/Kg;
mouse parenteral LDLo: 2.947mg/Kg;
pig intraduodenal LDLo: 1.58mg/Kg;
pig intravenous LDLo: 0.23mg/Kg;
pigeon intravenous LDLo: 0.337mg/Kg;
pigeon parenteral LDLo: 0.45mg/Kg;
rabbit intravenous LD50: 3.56mg/Kg;
rat intraperitoneal LD50: 4mg/Kg;
rat intravenous LD50: 25mg/Kg;
rat oral LD50: 28.27mg/Kg;
rat subcutaneous LD50: 0.0089mg/Kg;
rat rectal LDLo: 5mg/Kg.
reproductive effect.
Human toxicity[1]: child oral TDLo: 0.054mg/Kg;
child oral TDLo: 0.127mg/Kg;
infant intravenous LDLo: 0.2mg/Kg;
infant intravenous TDLo: 0.05mg/Kg;
man oral TDLo: 0.075mg/Kg;
man oral TDLo: 0.333mg/Kg;
women oral TDLo: 0.1mg/Kg;
women oral TDLo: 0.165mg/Kg/33D-;
women oral TDLo: 0.5mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent emulsifying, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 20830-75-5

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