Tobramycin
time:2015-07-03 21:48:30,count:0

Tobramycin
Alias
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1-4))-2-deoxy-
Category
Non-ionic surfactants-Sugar
CAS No.
32986-56-4
Molecular Formula & Molecular Weight
Molecular Formula: C18H37N5O9
Molecular Weight: 467.51
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intramuscular LD50: 440mg/Kg;
mouse intraperitoneal LD50: 445mg/Kg;
mouse intravenous LD50: 72.5mg/Kg;
mouse oral LD50: > 11500mg/Kg;
mouse subcutaneous LD50: 367mg/Kg;
rat intramuscular LD50: 913mg/Kg;
rat intraperitoneal LD50: 1030mg/Kg;
rat intravenous LD50: 104mg/Kg;
rat oral LD50: > 7500mg/Kg;
rat subcutaneous LD50: 969mg/Kg;
pig subcutaneous LD50: 676mg/Kg.
reproductive effect.
Human toxicity[1]: man intravenous TDLo: 37.714mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent antimicrobial, antibacterial abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
Actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient (antibiotic).
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 32986-56-4

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