Dextropropoxyphene hydrochloride
time:2015-07-08 22:31:46,count:0

Dextropropoxyphene hydrochloride
Alias
Benzeneethanol, alpha-((1R)-2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, 1-propanoate, hydrochloride (1:1), (alphaS)-
Category
Non-ionic surfactants-Amine
CAS No.
1639-60-7
Molecular Formula & Molecular Weight
Molecular Formula: C22H30ClNO2
Molecular Weight: 375.93
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: mouse intraperitoneal LD50: 111mg/Kg;
mouse intravenous LD50: 25mg/Kg;
mouse oral LD50: 225mg/Kg;
mouse subcutaneous LD50: 170mg/Kg;
dog intramuscular LD50: 65mg/Kg;
dog intraperitoneal LD50: > 38mg/Kg;
dog intravenous LD50: 29mg/Kg;
dog oral LD50: 100mg/Kg;
rabbit oral LD50: 82mg/Kg;
rat intramuscular LD50: 157mg/Kg;
rat intraperitoneal LD50: 58mg/Kg;
rat intravenous LD50: 15mg/Kg;
rat oral LD50: 84mg/Kg;
rat subcutaneous LD50: 134mg/Kg.
Human toxicity[1]: child oral LDLo: 70mg/Kg;
child oral TDLo: 27mg/Kg;
man oral TDLo: 11mg/Kg;
man oral TDLo: 37mg/Kg;
women oral LDLo: 15mg/Kg;
women oral TDLo: 0.0013mg/Kg;
women oral TDLo: 0.65mg/Kg;
women oral TDLo: 90mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent neuroleptic, antistatic, dispersing, emulsifying abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 1639-60-7

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