Danazol
time:2015-07-13 23:01:14,count:0

Danazol
Alias
Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol, (17alpha)-
Category
Non-ionic surfactants-Amine
CAS No.
17230-88-5
Molecular Formula & Molecular Weight
Molecular Formula: C22H27NO2
Molecular Weight: 337.46
Structural Formula
Properties
Appearance: solid.
Solubility: insoluble in water.
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: dog oral LD50: > 5000mg/Kg;
mouse intraperitoneal LD50: 6770mg/Kg;
mouse oral LD50: 4830mg/Kg;
mouse subcutaneous LD50: > 10000mg/Kg;
rabbit oral LD50: > 5000mg/Kg;
rat intraperitoneal LD50: > 10000mg/Kg;
rat oral LD50: > 17000mg/Kg;
rat subcutaneous LD50: > 10000mg/Kg.
reproductive effect.
Human toxicity[1]: man oral TDLo: 274mg/Kg/32D-;
man oral TDLo: 1029mg/Kg/17W;
women oral TDLo: 120mg/Kg/10D-;
women oral TDLo: 974mg/Kg/23W-.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent anti-estrogenic, antistatic, emulsifying, dispersing abilities. Hormone.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 17230-88-5

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