Bupivacaine
time:2015-07-14 15:06:50,count:0

Bupivacaine
Alias
2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-
Category
Non-ionic surfactants-Amine
CAS No.
38396-39-3
Molecular Formula & Molecular Weight
Molecular Formula: C18H28N2O
Molecular Weight: 288.43
Structural Formula
Properties
Appearance: solid.
Solubility: soluble in water; 25℃, 2.4g/L[1].
Stability: stable.
Risk: irritation, irritation to skin, eye.
Animal toxicity[1]: guinea pig intraperitoneal LD50: 36.6mg/Kg;
mouse intravenous LD50: 7.1mg/Kg;
mouse subcutaneous LD50: 35mg/Kg;
rabbit intratracheal LD50: 12.5mg/Kg;
rabbit intravenous LD50: 1.62mg/Kg;
rabbit parenteral LD50: 64mg/Kg;
rat intravenous LD50: 5.6mg/Kg;
rat subcutaneous LD50: 47mg/Kg.
reproductive effect.
Human toxicity[1]: human intravenous TDLo: 4.3mg/Kg.
Ecology: may be hazardous to environment. Water body should be given special attention.
Biodegradability: biodegradable.
Characteristics: excellent local anesthetic, antistatic, emulsifying, dispersing abilities.
Synthesis
 
Quality standards & test methods
item
physical and chemical indexes
test methods
actives*, %, ≥
95
 
*: should be marked on molecular weight.
Major Uses
Use as pharmaceutical ingredient.
Manufacturers
 
References
[1]:http://toxnet.nlm.nih.gov/: 38396-39-3

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